Fig. 3.

The NAC conformation of BDP in LinBwt viewed from the main tunnel (left) and from the p3 tunnel (right). The cleaved halide (chlorine) of BDP is situated in the middle of the aromatic ring system which causes parts of the molecule to bind to the p3 region while the other side fills the active site almost completely. BDP is shown as spheres, and residues within 4 Å from BDP and the in LinB32 and LinB86 mutated residues are shown as sticks following color scheme of Fig. 1. BDP is shown with the following color scheme: purple = chlorine, cyan = carbon, light cyan = fluorine, blue = nitrogen and white = hydrogen. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)