Table 2A.

Clinical features and comparison between the 2 IBD severity groups with regard to infectious and digestive complications.

		All patients	Mild patients	Severe patients	p *
General parameters
Duration of follow up (years)					0.323
	Mean (SD)	19.1 (2.6)	19.3 (2.8)	18.9 (2.7)
	Median (P25;P75)	20.2 (20.1;20.3)	20.3 (20.2;20.8)	20.2 (18.8;20.2)
Sex ratio		3F/6M	1F/4M	2F/2M	0.343
Age at onset (years)
GSD1B diagnosis	Mean (SD)	0.8 (1.1)	1.2 (1.3)	0.3 (0.3)	0.064
	Median (P25;P75)	0.6 (0.2;0.7)	0.7 (0.6;1)	0.2 (0.1;0.3)
Neutropenia	Mean (SD)	2.4 (3.5)	3.9 (4.2)	0.4 (0 0.2)	0.046
	Median (P25;P75)	0.7 (0.3;1.5)	1.5 (0.8;8.3)	0.3 (0.3;0.4)
Digestive symptoms	Mean (SD)	3.8 (3.4)	6 (3.3)	1.2 (0.4)	0.014
	Median (P25;P75)	2.1 (1.3;8)	8 (2.7;8.5)	1.3 (1.1;1.4)
First hospitalization	Mean (SD)	3 (3.6)	4.6 (4.2)	0.9 (0.6)	0.142
	Median (P25;P75)	1.3 (0.8;3.3)	3.3 (1;7.8)	1 (0.6;1.4)
Number of hospitalizations (/year)
Total	Mean (SD)	0.7 (0.6)	0.2 (0.2)	1.2 (0.4)	0.014
	Median (P25;P75)	0.5 (0.2;1.1)	0.2 (0.05;0.4)	1.3 (1;1.5)
For digestive reasons	Mean (SD)	0.4 (0.5)	0.05 (0.05)	0.8 (0.4)	0.012
	Median (P25;P75)	0.1 (0.05;0.6)	0.05 (0;0.1)	0.6 (0.6;0.8)
For infections	Mean (SD)	0.4 (0.3)	0.2 (0.2)	0.7 (0.1)	0.014
	Median (P25;P75)	0.4 (0.2;0.7)	0.2 (0.05;0.3)	0.8 (0.7;0.8)
Number of infectious episodes (/year) (regardless if hospitalization needed or not)					0.142
	Mean (SD)	1.8 (1.3)	1.3 (1.5)	2.4 (0.8)
	Median (P25;P75)	1.3 (0.7;2.7)	0.7 (0.6;1.1)	2.5 (2;2.8)