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. 2020 Mar 25;18:814–820. doi: 10.1016/j.csbj.2020.03.020

Fig. 4.

Fig. 4

Sensitivity of models for identifying efficient gRNAs in human gRNA libraries. The bar charts represent the percentage of efficient gRNAs identified by different models for each CRISPR library, namely Dolcetto (n = 55,521) for CRISPRi (a), Calabrese (n = 16,254) for CRISPRa (b), Brunello (n = 76,442) for Cas9 (c), and Mini human (n = 1963) for Cas12a (d). In each plot, the models are shown along the x-axis, and the sensitivity (the percentage of efficient gRNAs identified) is shown on the y-axis.