Table 2.

Comparison of Amino Acid and DRMs Detected by Sanger and NGS

Mutations		PR/RT	IN
AA mutations	Shared mean	9.45	10.70
	Unique Sanger mean	0.36	0.46
	Unique NGS mean	1.72	1.96
	P value	<0.001	<0.001
DRMs	Shared mean	0.37	0.30
	Unique Sanger mean	0.03	0.00
	Unique NGS mean	0.08	0.08
	P value	0.007	0.04

AA, amino acid; DRM, drug resistance mutation; IN, integrase; NGS, next-generation sequencing; PR/RT, protease/reverse transcriptase.