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. 2019 Aug 30;21:136–145. doi: 10.1016/j.jot.2019.07.006

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Microsphere size and morphology characterisation. (A) Size distribution histogram (interval = 0.5 μm) of all formulations of microparticles (n = 100). The average microsphere diameter and standard deviation (Ø) and the encapsulation efficiency of the respective antibiotics (EE%) are noted on every histogram. (B) Representative SEM images of PDLLA-GEN-AOT-HSM (I), PDLLA-GEN-AOT-SON (II), PCL-GEN-AOT-HSM (III) and PCL-GEN-AOT-SON (IV). Gen-AOT = gentamicin-dioctyl sulfosuccinate; PCL = poly(ɛ-caprolactone); SEM = scanning electron microscopy; SON = probe sonication; PDLLA = poly(D,l-lactic acid).