Table 2.
Dyspnea assessment, chest auscultation, pulmonary function, and CT scan findings of A(H7N9) survivors in follow-up visits.a
| Variable | 3-months | 6-months | 12-months | 18-months | 64-months |
|---|---|---|---|---|---|
| Dyspnea assessment | |||||
| No. of patients | 23 | 45 | 34 | 5 | 1 |
| No. of patients with mMRC dyspnea scale ≥1 | 17 | 25 | 18 | 5 | 1 |
| mMRC dyspnea scaleb | 1·47 ± 0·80 | 1·40 ± 0·58 | 1·16 ± 0·38 | 1·00 ± 0·00 | 1·00 ± 0·00 |
| Chest auscultation findings | |||||
| No. of patients | 24 | 40 | 34 | 7 | 3 |
| Moist rales | 3 (12·5) | 6 (15·0) | 3 (8·8) | 0 (0·0) | 0 (0·0) |
| Wheezes | 1 (4·2) | 0 (0·0) | 0 (0·0) | 0 (0·0) | 0 (0·0) |
| Rales and wheezes | 1 (4·2) | 1 (2·5) | 0 (0·0) | 0 (0·0) | 0 (0·0) |
| Coarse breath sounds | 1 (4·2) | 1 (2·5) | 5 (14·7) | 0 (0·0) | 0 (0·0) |
| Pulmonary function testing results | |||||
| No. of patients | 21 | 38 | 23 | 12 | 3 |
| Total ventilation dysfunction | 12 (57·1) | 14 (37·8) | 12 (52·1) | 5 (41·7) | 1 (33·3) |
| Obstructive | 3 (14·3) | 5 (13·5) | 4 (17·4) | 0 (0·0) | 0 (0·0) |
| Restrictive | 8 (38·1) | 7 (18·9) | 5 (21·7) | 3 (25·0) | 1 (33·3) |
| Mixed | 1 (4·8) | 2 (5·4) | 3 (13·0) | 2 (16·7) | 0 (0·0) |
| Diffusion dysfunction | 9/12 (75·0) | 17/27 (62·7) | 9/13 (69·2) | 4/7 (57·1) | 3 (100·0) |
| Chest CT scans | |||||
| No. of patients | 18 | 38 | 31 | 12 | 3 |
| Ground-glass opacities | 12 (66·7) | 28 (73·7) | 21 (67·7) | 8 (66·7) | 2 (66·7) |
| Nodule | 4 (22·2) | 2 (5·3) | 3 (9·7) | 1 (8·3) | 0 (0·0) |
| Bullous cysts | 1 (5·6) | 7 (18·4) | 7 (22·6) | 0 (0·0) | 1 (33·3) |
| Fibrosis | 3 (16·7) | 7 (18·4) | 6 (19·4) | 0 (0·0) | 0 (0·0) |
| Liner Fibrosis | 0 (0·0) | 0 (0·0) | 3 (9·7) | 8 (66·7) | 0 (0·0) |
| Pleural thickening | 2 (11·1) | 5 (13·2) | 6 (19·4) | 3 (25·0) | 0 (0·0) |
| Pleural effusion | 1 (5·6) | 2 (5·3) | 0 (0·0) | 0 (0·0) | 0 (0·0) |
| Calcification | 1 (5·6) | 2 (5·3) | 1 (3·2) | 0 (0·0) | 1 (33·3) |
| Increased lung marking | 1 (5·6) | 1 (2·6) | 0 (0·0) | 5 (41·7) | 0 (0·0) |
| Parenchymal opacification | 0 (0·0) | 0 (0·0) | 1 (3·2) | 1 (8·3) | 0 (0·0) |
a
Figures are No. (%) unless stated otherwise. If Indicates denominators for testing of fewer cases than full group, will be listed. NA, not applicable.
b
modified Medical Research Council dyspnea scale, mean ± SD, statistical description for mMRC ≥1.