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. 2020 Feb 10;20:100268. doi: 10.1016/j.eclinm.2020.100268

Table 3.

Characteristics of patients with failure and relapse.

Characteristic Failure
Relapse
P-value
N % N %
Total 60 100.0 14 100.0
Sex Male 39 65.0 11 78.6 0.33
Female 21 35.0 3 21.4
Age (years)a >=35 38 63.3 10 71.4 0.57
<35 22 36.7 4 28.6
HIV status Negative 51 85.0 14 100.0 0.12
Positive 9 15.0 0 0.0
Category New 55 91.7 13 92.9 0.88
Retreatment 5 8.3 1 7.1
BMI ≥18.5 20 33.3 3 21.4 0.39
<18.5 40 66.7 11 78.6
Lung lesionsb <50% 16 27.1 2 13.3 0.32
≥50% 43 72.9 12 85.7
FLQ Susceptible 32 76.2 11 91.7 0.47
Low-level resistant 2 4.8 0 0.0
High-level resistant 8 19.0 1 8.3
SLID Susceptible 43 97.7 12 100.0 1
Resistant 1 2.3 0 0.0
INH Susceptible 1 2.2 0 0.0 1
Resistant 44 97.8 11 100.0
PZA Susceptible 9 33.3 2 33.3 1
Resistant 18 66.7 4 66.7
PTH Susceptible 2 12.5 0 0.0 1
Resistant 14 87.5 5 100.0
EMB Susceptible 1 12.5 0 0.0 1
Resistant 7 87.5 1 100.0

BMI: body mass index in kg/m2; FLQ: fluoroquinolones; SLID: second-line injectable drugs; INH: isoniazid; PZA: pyrazinamide; PTH: prothionamide/ethionamide; EMB: ethambutol.

Numbers do not add up to column totals if there are missing data. The percentages refer to the displayed values excluding any missing. This is the case for Lung lesions among failures and for all drug susceptibility test results.

a

Mean (median) age 33.9 (31.0) and 30.8 (28.0) for failure and relapse cases, respectively.

b

Each lung has been divided into three zones (superior, middle, inferior) by dividing the space between apex and hemi-diaphragm into three. The extent of lung lesions is defined as the proportion of zones affected among the 6 zones.