Table 3.
Characteristics of patients with failure and relapse.
| Characteristic | Failure |
Relapse |
P-value | |||
|---|---|---|---|---|---|---|
| N | % | N | % | |||
| Total | 60 | 100.0 | 14 | 100.0 | ||
| Sex | Male | 39 | 65.0 | 11 | 78.6 | 0.33 |
| Female | 21 | 35.0 | 3 | 21.4 | ||
| Age (years)a | >=35 | 38 | 63.3 | 10 | 71.4 | 0.57 |
| <35 | 22 | 36.7 | 4 | 28.6 | ||
| HIV status | Negative | 51 | 85.0 | 14 | 100.0 | 0.12 |
| Positive | 9 | 15.0 | 0 | 0.0 | ||
| Category | New | 55 | 91.7 | 13 | 92.9 | 0.88 |
| Retreatment | 5 | 8.3 | 1 | 7.1 | ||
| BMI | ≥18.5 | 20 | 33.3 | 3 | 21.4 | 0.39 |
| <18.5 | 40 | 66.7 | 11 | 78.6 | ||
| Lung lesionsb | <50% | 16 | 27.1 | 2 | 13.3 | 0.32 |
| ≥50% | 43 | 72.9 | 12 | 85.7 | ||
| FLQ | Susceptible | 32 | 76.2 | 11 | 91.7 | 0.47 |
| Low-level resistant | 2 | 4.8 | 0 | 0.0 | ||
| High-level resistant | 8 | 19.0 | 1 | 8.3 | ||
| SLID | Susceptible | 43 | 97.7 | 12 | 100.0 | 1 |
| Resistant | 1 | 2.3 | 0 | 0.0 | ||
| INH | Susceptible | 1 | 2.2 | 0 | 0.0 | 1 |
| Resistant | 44 | 97.8 | 11 | 100.0 | ||
| PZA | Susceptible | 9 | 33.3 | 2 | 33.3 | 1 |
| Resistant | 18 | 66.7 | 4 | 66.7 | ||
| PTH | Susceptible | 2 | 12.5 | 0 | 0.0 | 1 |
| Resistant | 14 | 87.5 | 5 | 100.0 | ||
| EMB | Susceptible | 1 | 12.5 | 0 | 0.0 | 1 |
| Resistant | 7 | 87.5 | 1 | 100.0 | ||
BMI: body mass index in kg/m2; FLQ: fluoroquinolones; SLID: second-line injectable drugs; INH: isoniazid; PZA: pyrazinamide; PTH: prothionamide/ethionamide; EMB: ethambutol.
Numbers do not add up to column totals if there are missing data. The percentages refer to the displayed values excluding any missing. This is the case for Lung lesions among failures and for all drug susceptibility test results.
Mean (median) age 33.9 (31.0) and 30.8 (28.0) for failure and relapse cases, respectively.
Each lung has been divided into three zones (superior, middle, inferior) by dividing the space between apex and hemi-diaphragm into three. The extent of lung lesions is defined as the proportion of zones affected among the 6 zones.