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. 2020 Apr 12;61:126508. doi: 10.1016/j.jtemb.2020.126508

Table 2.

Vanadium-containing biomaterials and their use in medical devices.

Metallic biomaterials
Type of alloy Percentage composition [%] Application Reference
Ti-6Al-4V Ti 90 Al 6 V 4 hip joint replacement
knee joint replacement
dental implants (zygomatic implants), bridges/crowns, dental bridges
orthodontic implants
spine stabilizers
trauma devices/bone fixation (intramedullary rods and nails, surgical screws/bone plates)
encapsulation of cardiac pacemaker
[11,13,111,112,113,114,115,116,117,118,119]
Ti-6Al-4V ELI Ti 90 Al 6 V 4 medical implants [11,13]
Ti-3Al-2.5V Ti 92.755−95.5 Al 2.5−3.5 V 2−3 dental implants
hip and knee joint replacement (orthopedic implants)
trauma devices (intramedullary rods)
[11]
Magnetic alloys
2V-49Co-49Fe (Permendur) Co 49 Fe 49 V 2 devices supporting the work of the heart [11]
Biocompatible coatings applied on metallic alloys
TiO2:nHA:Ag-Ti-6Al-4V
SC-Ti-6Al-4V
V-DLC
Ti 90 Al 6 V 4
Ti 90 Al 6 V 4
orthopedic/dental implants
hip joint replacement
trauma/orthopedic surgery
[11,120,121]
Polymeric composite biomaterials
Composition of polymeric coating Properties Application Reference
V2O5/PLGA antimicrobial activity implant materials [122]

Ti: titanium; Al: aluminum; V: vanadium, ELI: extra low interstitial (max. Fe: 0.14 %, max. O: 0.13 %). TiO2:nHA:Ag-Ti-6Al-4V: titanium oxide-based coating containing hydroxyapatite nanoparticle and silver particles, SC-Ti-6Al-4V: surface-coated Ti-6Al-4 V, V-DLC: diamond-like layer with vanadium (DLC type carbon layer), V2O5: vanadium pentoxide; PLGA: (Poly)Lactide-co-Glycolide copolymer.