Table 2.
Highest scoring molecules for SARS-CoV-2 3CLPRO Main Protease.
| Site # | DrugBank ID | Docking Score (kcal/mol) | Name | Indication |
|---|---|---|---|---|
| 1 | DB00157 | −11.016 | Dpnh (NADH) | Supplement Mental Health |
| 1 | DB00558 | −8.843 | Zanamivir | Antiviral Drug |
| 1 | DB00188 | −8.654 | Bortezomib | Anti-Cancer |
| 1 | DB01232 | −7.285 | Saquinavir | HIV Protease Inhibitor |
| 2 | DB03147 | −10.339 | Flavin Adenine Dinucleotide (FAD) Adeflavin | B2 Deficiency |
| 2 | DB06441 | −10.269 | Cangrelor | P2Y12 Inhibitor |
| 2 | DB08889 | −8.924 | Carfilzomib | Anti-Cancer |
| 2 | DB00224 | −8.199 | Indinavir | HIV Protease Inhibitor |
| 2 | DB14761 | −7.215 | Remdesivir | Antiviral |