Fig. 2.

Proteins associated with tubular carriers in mammalian cells. Models from experimental data on different types of secretory tubular carriers that bud towards the plasma membrane in mammalian cells. The carriers have been drawn as separate entities unless there is strong experimental evidence to combine the carriers. Some of the machinery described here might be overlapping on the same carriers, for example the SM carriers and CARTS, and the LAMP1-RUSH carriers, Rab6 carriers and the Arf1 carriers. Protein cartoons are not to scale and do not meaningfully reflect protein structure. LYZ = Lysozyme C.