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HPLC analysis of digests of DMC-oligonucleotide complexes formed under DMC autocatalytic activation (A and B) and bifunctional activation (C and D). Oligonucleotides used: duplex 5’-ATATAGCTATAT-3’ (A and C) and duplex 5’-ATATACGTATAT-3’ (B and D). 4: adenine adduct.25
