(b) Pathways of downregulated DEGs
| ID | Pathway | Count | P-value | Adj.P-Val |
|---|---|---|---|---|
| Downregulated | ||||
| R-HSA:209968 | Thyroxine biosynthesis | 4.00 | 1.02232E-06 | 2.2491E-05 |
| R-HSA:209776 | Amine-derived hormones | 4.00 | 1.41298E-05 | 0.000296725 |
| R-HSA:5661231 | Metallothioneins bind metals | 3.00 | 9.55155E-05 | 0.00191031 |
| R-HSA:5660526 | Response to metal ions | 3.00 | 0.000206804 | 0.00392928 |
| KEGG:00350 | Tyrosine metabolism | 4.00 | 0.000241586 | 0.004348555 |
| R-HSA:3560782 | Diseases associated with glycosaminoglycan metabolism | 4.00 | 0.000401916 | 0.006832565 |
| R-HSA:2161282 | Elastic fibres bind associated proteins | 3.00 | 0.000452188 | 0.007235015 |
| R-HSA:1630316 | Glycosaminoglycan metabolism | 6.00 | 0.000673119 | 0.01009678 |
| KEGG:04978 | Mineral absorption | 4.00 | 0.000928833 | 0.013003667 |
| WP:2895 | Differentiation of white and brown adipocyte | 3.00 | 0.001220241 | 0.01586313 |
(a) Pathways of upregulated DEGs. (b) Pathways of downregulated DEGs.