Figure 8.

Expression of mitophagy-associated proteins, Keap1 and Nrf2, is regulated by rhSTC1 in rat kidney. Rats were treated as mentioned above. (a, b) Western blot was used to detect the expression of mitophagy-associated proteins, Keap1 and Nrf2 (n = 3). (c–j) Quantification of average Western blot band intensities. (k) Kidney sections from the mentioned groups were stained with PINK1, Parkin, LC3II, P62, Nrf2, and Keap1 antibodies for IHC analysis (magnification, ×400). Values were presented as mean ± SE. ^∗p < 0.05, compared with the control group. ^#p < 0.05, compared with the CI-AKI group.