Skip to main content
. 2020 Mar 13;11(4):433–438. doi: 10.1021/acsmedchemlett.9b00508

Table 1. In Vitro Activity of Sulfamoylo Derivatives.

graphic file with name ml9b00508_0007.jpg

Cmpd x n R1 R2 R3 ARG1 IC50 (μM)
1 Reference compound 0.12
2 Reference compound 1.2
11a NH 1 H H H 0.33
11b NH 1 Me H H 2.3
11c NH 1 H Me Me 0.73
11d NH 1 H H Me 1.0
11e NH 1 H H Bn 1.4
12 NH 2 H H H 2.8
13 CH2 1 H H H 1.1