Table 3.
Top 10 frequent criterion patterns used by the 57 trials, separated by inclusion vs. exclusion.
| Rank | Inclusion Criterion Pattern | Study Coverage # of Studies (%) | Exclusion Criterion Pattern | Study Coverage # of Studies (%) |
| N = 57 | N = 57 | |||
| 1 | Aspartate aminotransferase (AST) | 32 (56.14%) | Unstable angina | 36 (63.16%) |
| 2 | Measurable disease | 29 (50.88%) | Myocardial infarction | 34 (59.65%) |
| 3 | Age | 29 (50.88%) | Radiotherapy | 30 (52.63%) |
| 4 | Absolute neutrophil count | 29 (50.88%) | Congestive heart failure | 26 (45.61%) |
| 5 | Platelets | 27 (47.36%) | Pregnant | 22 (38.60%) |
| 6 | Metastatic colorectal cancer | 27 (47.36%) | Bone fracture | 22 (38.60%) |
| 7 | Hemoglobin | 25 (43.86%) | Significant traumatic injury | 22 (38.60%) |
| 8 | Bilirubin | 22 (38.60%) | Bleeding diathesis | 21 (36.84%) |
| 9 | Creatinine | 22 (38.60%) | Chemotherapy | 20 (35.09%) |
| 10 | Alanine transaminase (ALT) | 20 (35.09%) | Skin ulcers | 20 (35.09%) |