Figure 3.
Characteristics of GR-binding sites for each cell type. (A) Number of GR binding sites within and beyond 20kb of TSS of annotated genes. (B) Proportion of GR binding sites according to type of genomic region. (C) Genes with GR-binding that have (green) vs. do not have (blue) active transcription in response to glucocorticoid exposure as determined by RNAP2 or microarray results. ASM: airway smooth muscle; Beas-2B: airway epithelial cells; A549: adenocarcinomic alveolar epithelial cells; RS4;11: acute lymphoblastic leukemia cells; LCL: lymphoblastoid cell lines.