Table 1.
List of glycosaminoglycans and peptides in ECM mimetic substrates.
Glycosaminoglycans (GAGs) | ||
---|---|---|
Heparin (Hep) | ||
Heparan Sulfate (Hepa) | ||
Chondroitin Sulfate (Chon) | ||
Dermatan Sulfate (Derm) | ||
Dextran Sulfate (Dext) | ||
Peptide |
Description |
Amino acid sequence |
KA7 | GAG-binding motif (Lys-Ala repeats) with cysteine residue for starPEG conjugation (40) | CWGGKAKAKAKAKAKAKA |
RGD | Arg-Gly-Asp (RGD) is a cell adhesion sequence in many ECM proteins (42) | (KA7)-RGDSP |
AG73 | ECM protein laminin-derived cell adhesion peptide (43) | (KA7)-RKRLQVQLSIRT |
F2A | Fibroblast growth factor mimetic peptide (44) | (KA7)-HYRSRKYSSWYVALKR |
R9 | Polyarginine cell penetrating peptide (45) | (KA7)-RRRRRRRRR |