Table 5.
Summary of nanoradiosensitizers based on autophagy mechanism.
| Composition | Size (nm) | Surface Chemistry | Cell Line/Model | Source Energy | DEF/SER/Effect | Ref. |
|---|---|---|---|---|---|---|
| Silver | 27 | N.A. | U251 | 0–8 Gy | 1.78 | [177] |
| Fe3O4@Ag | 11 | N.A. | U251 | 0–8 Gy | 1.80 | [178] |
| Gadolinium oxide | 2–5 | N.A. | A549, NH1299, NH1650 | 0–4 Gy | 1.10 (A549), 1.11 (NH1299), 1.20 (NH1650) | [125] |
| Copper cysteamine | N.A. | N.A. | SW620 | 1–4 Gy | Increased cell death | [179] |
| CuO | 5.4 | N.A. | MCF-7 cells, U14 tumor-bearing nude mice | 0–8 Gy | Increased cell death | [49] |
| FePt/GO | 3 | N.A. | H1975 | 0–8 Gy | Inhibited tumor growth | [180] |
Abbreviations: DEF, dose enhancement factor; SER, sensitization enhancement ratio; N.A., not available; Ref., references.