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. 2020 Feb 5;11(4):566–574. doi: 10.1021/acsmedchemlett.0c00030

Table 2. Mean Percentage of Cells Showing Early Apoptosis, Late Apoptosis, and Necrosis after Exposure to 1/2 MIC Values of the Most Active Compounds for 3 ha.

  % cell population with different effects after 3 h exposure
Comp. (MIC) Annexin V+/PI– (early apoptosis) Annexin V+/PI+ (late apoptosis) Annexin V–/PI+ (necrosis)
Negative control 3.47 ± 0.26 0.06 ± 0.01 0.15 ± 0.03
Positive control 27.60 ± 2.76 26.43 ± 0.54 2.31 ± 0.01
6d 10.18 ± 0.58 15.60 ± 0.65 3.70 ± 0.22
6e 13.90 ± 0.53 23.60 ± 0.97 1.78 ± 0.11
6f 8.21 ± 1.82 48.30 ± 1.97 9.80 ± 0.32
6g 10.49 ± 0.76 27.92 ± 2.13 2.44 ± 0.08
6h 8.23 ± 1.08 44.65 ± 2.76 11.70 ± 0.34
6i 13.37 ± 0.69 36.34 ± 2.97 1.98 ± 0.97
6j 9.69 ± 0.95 24.93 ± 2.11 4.55 ± 0.79
a

2.5 mM H2O2 was used as a positive control.