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. 2019 Nov 15:421–450. doi: 10.1016/B978-0-12-814338-4.00011-8

Table 11.1.

Physical Findings.

Abnormality Potential Diagnosis
Pale mucous membranes, extremities, or eyes Anemia (if rat appears otherwise relatively normal)
Excessive or too frequent blood collection
Circulatory deficiency (if animal appears weak or depressed)
Alopecia with normal, intact skin Physical abrasion from cage or feeder
Self-grooming or barbering from cage mate
Alopecia with crusted, inflamed, or ulcerated skin Ectoparasites or dermatophytes
Bacterial opportunists such as Staphylococcus aureus
Pruritic syndromes
Dermal or subcutaneous masses Tumors of skin or mammary origin
Lymphadenopathy
Abscess, granuloma, cyst
Nodular deformity of ears Auricular chondritis
“Red” or “bloody” tears Chromodacryorrhea caused by Harderian gland secretions (can also be seen on front paws and over the back from grooming)
Frequent clinical sign of coronaviral infection but can also be a nonspecific finding of illness or distress
Circumferential, annular constrictions on tail Ringtail (generally seen in suckling animals under conditions of low humidity and a cool or poorly insulated environment)
Head tilt, circling or spinning when lifted by tail Bacterial or mycoplasmal otitis interna/media
Tumor or other space-occupying brain lesion
Hairless, swollen, or bleeding plantar lesions “Sore hock” syndrome associated with large and/or aged rats kept on wire or mesh flooring
Salivation, weight loss, swollen oral tissues Malocclusion
Fecal staining Diarrheal enteritis
Dyspnea/rales/hyperventilation Mycoplasma pulmonis, Filobacterium rodentium (formerly CAR bacillus), Corynebacterium kutscheri, or Streptococcus pneumoniae infection
Overheating
Facial swellings Parotid and/or submandibular salivary gland swelling from coronavirus infection
Abscess of lymph nodes (lymphadenitis)
Zymbal gland tumor at the base of the ear
Abdominal distension (pot-bellied appearance) Ascites
Intestinal distension from toxicity (chloral hydrate)
Enteritis (possibly megaloileitis associated with Tyzzer's disease)
Obesity
Abdominal mass (tumor, abscess)
Pregnancy
Excessively wet hair coat and/or bedding Diabetic polyuria
Leaking bottle or automatic water system
Behavioral water wastage from “playing”
Overheating
Eye lesions Blepharospasm, corneal opacities, keratitis due to coronaviral infection
Cataracts (aging lesion)