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. 2019 Nov 8:225–261. doi: 10.1016/B978-0-12-816331-3.00007-6

Table 7.2.

Frequency of monoclonal antibody-resistant mutants (MARMs) for some viruses.

Virus Monoclonal antibody-resistant mutant (MARM) frequencies References
Poliovirus 10−4 to 10−5 Emini et al. (1982) and Minor et al., 1983, Minor et al., 1986
Mengovirus 3 × 10−3 to 5 × 10−5 Boege et al. (1991)
Foot-and-mouth disease virus 10−4 to 10−5 (continuous epitopes) Martínez et al. (1991a)
10−4 to 10−7 (discontinuous epitopes) Lea et al. (1994)
Rhinovirus 10−4 to 10−5 Sherry et al. (1986)
Hepatitis A virus 3 × 10−3 Stapleton and Lemon (1987)
Vesicular stomatitis virus 0.5 × 10−4 to 1 × 10−4 Holland et al. (1990)
Rabies virus 10–4 Wiktor and Koprowski (1980)
Measles virus 9 × 10−5 Schrag et al. (1999)
Sindbis virus 10−3 to 10−5 Stec et al. (1986)
Canine parvovirus 10−3.4 to 10−5.4 Smith and Inglis (1987)
Herpes simplex virus 1 × 10−5 Smith and Inglis (1987)