Table 7.2.
Frequency of monoclonal antibody-resistant mutants (MARMs) for some viruses.
Virus | Monoclonal antibody-resistant mutant (MARM) frequencies | References |
---|---|---|
Poliovirus | 10−4 to 10−5 | Emini et al. (1982) and Minor et al., 1983, Minor et al., 1986 |
Mengovirus | 3 × 10−3 to 5 × 10−5 | Boege et al. (1991) |
Foot-and-mouth disease virus | 10−4 to 10−5 (continuous epitopes) | Martínez et al. (1991a) |
10−4 to 10−7 (discontinuous epitopes) | Lea et al. (1994) | |
Rhinovirus | 10−4 to 10−5 | Sherry et al. (1986) |
Hepatitis A virus | 3 × 10−3 | Stapleton and Lemon (1987) |
Vesicular stomatitis virus | 0.5 × 10−4 to 1 × 10−4 | Holland et al. (1990) |
Rabies virus | 10–4 | Wiktor and Koprowski (1980) |
Measles virus | 9 × 10−5 | Schrag et al. (1999) |
Sindbis virus | 10−3 to 10−5 | Stec et al. (1986) |
Canine parvovirus | 10−3.4 to 10−5.4 | Smith and Inglis (1987) |
Herpes simplex virus | 1 × 10−5 | Smith and Inglis (1987) |