Table 7.2.

List of antigens delivered by nanocarriers for the treatment of different diseases in vaccine research.

Antigen	Nanocarrier used	Disease
Against Bacterial Infection
Antigenic protein	Poly(D,L-lactic-co-glycolic acid) nanospheres	Anthrax
DNA encoding T cell epitopes of Esat-6 and FL	Chitosan nanoparticle	Tuberculosis
Mycobacterium lipids	Chitosan nanoparticle	Tuberculosis
Polysaccharides	Liposomes	Pneumonia
Bacterial toxic and parasitic protein	Liposomes	Cholera and malaria
Fusion protein	Liposomes	Helicobacter pylori infection
Antigenic protein	Nanoemulsion	Cystic fibrosis
Antigenic protein	Nanoemulsion	Anthrax
Mycobacterium fusion protein	Liposome	Tuberculosis
Against Viral Infection
Antigenic protein	Chitosan nanoparticles	Hepatitis B
Viral protein	Gold nanoparticles	Foot and mouth disease
Membrane protein	Gold nanoparticles	Influenza
Viral plasmid DNA	Gold nanoparticles	HIV
Tetanus toxoid	Poly(D,L-lactic-co-glycolic acid) nanospheres	Tetanus
Hepatitis B surface antigen	Poly(D,L-lactic-co-glycolic acid) nanospheres	Hepatitis B
Hepatitis B surface antigen	Alginate-coated chitosan nanoparticle	Hepatitis B
Live virus vaccine	Chitosan nanoparticles	Newcastle disease
Capsid protein	VLPs	Norwalk virus infection
Capsid protein	VLPs	Norwalk virus infection
Influenza virus structural protein	VLPs	Influenza
Nucleocapsid protein	VLPs	Hepatitis
Fusion protein	VLPs	Human papilloma virus
Multiple proteins	VLPs	Rotavirus
Virus proteins	VLPs	Blue tongue virus
Enveloped single protein	VLPs	HIV
Viral protein	Polypeptide nanoparticles	Corona virus for severe acute respiratory syndrome (SARS)
Against Parasitic Infection
Merozoite surface protein	Iron oxide nanoparticles	Malaria
Epitope of Plasmodium berghei circumsporozoite protein.	Polypeptide nanoparticles	Rodent malarial parasitic infection
Surface protein from Eimeria falciformis sporozoites	ISCOMs	Diarrhea

From Pati R, Shevtsov M, Sonawane A. Nanoparticle vaccines against infectious diseases. Front Immunol 2018;9. adapted with permission.