Table 3.
Applied settings for single particle inductively coupled plasma mass spectrometry (spICP-MS) measurements with inductively coupled plasma mass spectrometry (ICP-MS)/MS.
| Instrument Parameter | Operation Settings | |
|---|---|---|
| Nebulizer | Micromist | |
| Spray chamber | Quartz, double pass | |
| Sampler and skimmer cones | Nickel | |
| Radio Frequency (RF) power (W) | 1550 | |
| Plasma gas flow (L min−1) | 15 | |
| Auxiliary gas flow (L min−1) | 0.90 | |
| Carrier gas flow (L min−1) | 1.04 | |
| Cell gas | 10% NH3/90% He | |
| Cell gas flow rate (mL min−1) | 2 | |
| Sample flow rate (mL min−1) | 0.47 ± 0.02 | |
| Sampling depth | Ti: 4.3 ± 0.4 Au: 6.6 ± 0.3 |
|
| Dwell time (ms) | 3 | |
| Sampling time (min) | 1 | |
| Transport efficiency (%) | 4.8 ± 0.9 | |
| Monitored element | Ti | Au |
| Isotope (amu) monitored at Q1–Q2 | 48–150 | 197–197 |
| Elemental composition of the target particle | TiO2 | Au |
| Density (g cm−3) | 4.23 | 19.3 |
| Mass fraction particle/analyte | 1.67 | 1.0 |
| Ionization efficiency (%) | 100 | 100 |