Table 3.

Panel of genes analysed by RT-qPCR in fat tissue of impaired glucose regulation (IGR) patients (n = 20) before and 6 months after the lifestyle intervention. The results are shown as average ± SE. * p ≤ 0.025

	Fold change mean ± SE			p value
Gene	(Before)	(After)	T value (paired T-test)	(*p ≤ 0.025)
PPARG	2.76 ± 0.9	1.62 ± 0.3	1.132	0.273
GIPR	2.96 ± 1.2	3.10 ± 0.6	−0.124	0.903
IGF2BP2	3.30 ± 1.3	2.30 ± 0.5	0.683	0.504
FTO	3.20 ± 0.7	1.81 ± 0.3	1.969	0.065
CAV1	1.85 ± 0.2	1.04 ± 0.1	2.263	0.025*
IGF1 R	1.70 ± 0.5	1.65 ± 0.4	0.066	0.948
INSR	1.70 ± 0.3	1.78 ± 0.5	−0.246	0.809
IGFBP4	3.30 ± 1.0	2.89 ± 0.6	0.431	0.672
WFS	2.91 ± 0.8	2.21 ± 0.5	0.820	0.424
IGF-I	2.01 ± 0.5	1.95 ± 0.4	0.089	0.930
LPL	9.90 ± 3.2	7.50 ± 2.0	0.817	0.426
IGFBP-2	1.65 ± 0.4	1.22 ± 0.1	1.161	0.262
IGF-II	3.71 ± 1.4	3.18 ± 0.8	0.451	0.658
IGFBP-6	2.60 ± 1.0	2.26 ± 0.4	0.338	0.739
LEP	15.4 ± 5.2	14.6 ± 4.6	0.124	0.903
LDLR	2.43 ± 1.0	1.04 ± 0.2	1.458	0.163
IGFR-2	2.30 ± 0.6	1.97 ± 0.4	0.759	0.458
HHEX	2.34 ± 0.5	2.22 ± 0.6	0.267	0.793