Table 2. A multivariate analysis of survival with clinic factors and the 7-lncRNA signature.

Variables	Univariate analysis		Multivariate analysis
	HR (95%CI)	P value	HR (95%CI)	P value
Age (>60 vs ≤60)	1.372 (0.843–2.233)	0.20284069
Gender (male vs female)	1.198 (0.779–1.843)	0.41154492
Pathologic stage (stage I/II vs stage III/IV)	3.486 (2.171–5.599)	2.39E−07*	3.859 (0.933–15.972)	0.06237977
LncRNA model scores (high score vs low score)	3.494 (2.148–5.683)	4.67E−07*	2.363 (1.306–4.275)	0.0044734*
T classification (T1/T2 vs T3/T4)	3.458 (1.397–8.559)	0.00730575*	2.827 (0.654–12.218)	0.16407723
N classification (N0 vs N1/N2)	3.042 (1.948–4.748)	9.87E−07*	0.470 (0.130–1.695)	0.24873161
M classification (M0 vs M1 vs MX)	5.383 (3.328–8.707)	6.82E−12*	2.190 (1.147–4.182)	0.01752146*
Venous invasion (yes vs no)	2.773 (1.742–4.415)	1.72E−05*	1.500 (0.772–2.915)	0.23181158
Lymphatic invasion (yes vs no)	2.414 (1.522–3.830)	0.00018109*	1.219 (0.610–2.436)	0.57420717

Notes.

Abbreviations

CI

confidence interval

HR

hazard ratio

lncRNA

long noncoding RNA

^*P value refers to the significant level in the χ² test.