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. Author manuscript; available in PMC: 2020 Apr 13.
Published in final edited form as: Cell Rep. 2020 Mar 17;30(11):3755–3765.e7. doi: 10.1016/j.celrep.2020.02.061

Figure 3. Polyclonal Antibody Responses of High Autologous Neutralizing Titer Macaques Immediately before SHIVBG505 Challenge.

Figure 3.

(A–F) Segmented 3D reconstructions of (A) 12–143, (B) 12–137, (C) 12M-169, (D) 11M-088, (E) 12–046, and (F) 4O9. The number in parentheses indicates the number of SHIVBG505 challenges it took for the animal to become infected (see Figure S3 for representative additional 3D phenotypes).

(G) Bar graph summary of the epitopes targeted by high autologous neutralizing titer macaques.

(H) Comparison of the angle of approach between bnAb PGT121 and animal 409 V1/V3 polyclonal response.