Table 2.
Placental diffusion metrics across healthy and high-risk pregnancies
| Control (n=97) | FGR (n=36) | p-valuea | ||
|---|---|---|---|---|
| Small Scale Diffusion (D) | 1.76 | 1.74 | 0.76 | |
| Large Scale Pseudo-Diffusion (D*) | 36.80 | 34.14 | 0.42 | |
| Perfusion Fraction (f, %) | 40.65 | 37.68 | 0.19 | |
| Control (n=97) | Early-Onset FGR (n=11) | Late-Onset FGR (n=25) | p-valueb | |
| Small Scale Diffusion (D) | 1.76 | 1.50 | 1.87c, d | <0.05 c,d |
| Large Scale Pseudo-Diffusion (D*) | 36.80 | 23.56 | 39.42d | <0.05 d |
| Perfusion Fraction (f, %) | 40.65 | 45.94 | 34.13c, d | <0.05 c,d |
| Control (n=97) | FGR, CPR >1 (n=21) | FGR, CPR <1 (n=15) | p-valueb | |
| Small Scale Diffusion (D) | 1.76 | 1.82 | 1.66 | NS |
| Large Scale Pseudo-Diffusion (D*) | 36.80 | 37.51 | 29.23 | NS |
| Perfusion Fraction (f, %) | 40.65 | 37.60 | 38.51 | NS |
| Control (n=97) | FGR, No MHD (n=31) | FGR, + MHD (n=05) | p-valueb | |
| Small Scale Diffusion (D) | 1.76 | 1.79 | 1.50 | NS |
| Large Scale Pseudo-Diffusion (D*) | 36.80 | 35.60 | 23.07 | NS |
| Perfusion Fraction (f, %) | 40.65 | 37.33 | 41.90 | NS |
a
Based on independent samples t-test
b
Pairwise comparisons based on least squares means estimates from ANOVA
c
significantly different from control at p < 0.05
d
significantly different from early-onset FGR at p < 0.05
Abbreviations: FGR=fetal growth restriction, CPR=cerebroplacental ratio, MHD=maternal hypertensive disorders (namely, gestational hypertension, chronic hypertension and preeclampsia)