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. Author manuscript; available in PMC: 2020 Apr 13.
Published in final edited form as: Sci Transl Med. 2015 Nov 18;7(314):314ra184. doi: 10.1126/scitranslmed.aad1904

Fig. 5. Idol regulates ApoE in the brain.

Fig. 5.

(A) Immunoblot analysis of total brain lysates from the frontal cortex of APP/PS1;Idol+/+ or APP/PS1;Idol−/− mice. Lanes represent samples from individual mice. (B to D) Immunoblot analysis of ApoE and tubulin protein in the (B) PBS-soluble fraction, (C) RIPA fraction, and (D) insoluble (guanidine) fraction from the frontal samples from individual mice. Quantification of the 0.05, **P < 0.01 by Student’s t test. Each experiment was cortex of APP/PS1;Idol+/+ or APP/PS1;Idol−/− mice. Lanes represent signals is presented on the right. Error bars represent SEM. *P < at least twice.