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. 2020 Mar 21;12(1):1738691. doi: 10.1080/19420862.2020.1738691

Figure 4.

Figure 4.

Results of SPR binding assay for detection of coaggregates of mAb-A and mAb-B. Positive control of coaggregates fractionated by HPSEC was obtained from a 1:1 mixture of mAb-A and mAb-B incubated at 50°C for 33 days (black solid line). Shown are aggregate fractions by HPSEC from nonstressed Combo (green solid line) and Combo incubated at 40°C for 3 months (green dotted line).