Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 25;12(1):1729683. doi: 10.1080/19420862.2020.1729683

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 4. — A surface epitope region (red) consisting of 12 different amino acids selected from the exposed surface of the protein, PCSK9 (PDB: 2PMW). An outline of each residue side-chain is indicated by a yellow circle or oval. The epitope region is used to calculate the combinations of each unique residue set from 1 to 12 residues that could be addressed by different antibodies. The surface region is redrawn from the PDB structure (2PMW; reference 75) using Adobe Illustrator See text for explanation.