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Results of the safety assessment from dose escalation PET imaging. The body weights of each group over the 7 d after administration (a). Histograms of liver (b) and spleen (c) uptake after intravenous injection of 89Zr-labeled IBI322. H&E staining of liver and spleen sections from each group. (Scale bar: 200 µm) (d). The black arrow indicates partially necrotic regions of the spleen.
