. Author manuscript; available in PMC: 2021 Jun 1.

Published in final edited form as: Biochim Biophys Acta Gen Subj. 2020 Feb 4;1864(6):129546. doi: 10.1016/j.bbagen.2020.129546

Table 2.

Potentiation of Erythromycin Activity by Top Hits in Efflux-proficient (WT-Pore) and Efflux-deficient (ΔTolC) Cells

ERY MIC (mg/L) in the presence of compounds at a given concentration (μM)
	WT-Pore					ΔTolC
compound	0	6.25	12.5	25	50	0	6.25	12.5	25	50
24123034	16	8	4	1	1	2	2	2	2	2
36287038	16	16	16	4	1–2	2	2	2	2	1
56871955	16	16	16	8	4	2	2	2	2	2
58997260	16	8	4	2	1	2	2	2	2	1
65071797	16	16	8	2–4	1	2	2	2	2	2
98577577	16	16	16	8	2–4	2	2	2	2	2