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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Biochim Biophys Acta Gen Subj. 2020 Feb 4;1864(6):129546. doi: 10.1016/j.bbagen.2020.129546

Table 3.

Potentiation of Novobiocin Activity by Top Hits in Efflux-proficient (WT-Pore) and –deficient (ΔTolC) Cells

NOV MIC (mg/L) in the presence of compounds at a given concentration (μM)
WT-Pore ΔTolC
compound 0 6.25 12.5 25 50 0 6.25 12.5 25 50
24123034 32 32 16 8 4 0.5 0.5 0.5 0.25 0.25
36287038 32 32 32 32 16 0.5 0.5 0.5 0.25 0.25
56871955 32 32 32 16 8 0.5 0.5 0.5 0.25 0.25
58997260 32 32 32 16 8 0.5 0.5 0.25 0.25 0.125
65071797 32 32 32 4 4 0.5 0.5 0.5 0.5 0.5
98577577 32 32 32 32 4 0.5 0.5 0.5 0.25 0.5