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. 2020 Feb 24;214(4):1103–1120. doi: 10.1534/genetics.119.302851

Table 2. MIC determinations for ONC201, ONC212, and ADEP1 against a panel of non-ESKAPE bacteria or mycobacteria.

Compound N. gonorrhoeae (WHOY) N. gonorrhoeae (ATCC 49226) M. smegmatis (mc2155) M. tuberculosis (H37Ra) E. coli (BW25113) E. coli (∆tolCbamB)
ONC201 (μM) 250–500 125–250 125–250 250–500 > 500 > 250
ONC212 (μM) 31.25–62.5 31.25–62.5 > 250 > 100 > 250 50–100
ADEP1 (μM) > 360

Strains are indicated in parentheses for each species. Dashes indicate not tested. ATCC, American Type Culture Collection.