Table 1. Quantification of the area under the curve (AUC) of Spen-KD and CTRL-KD on diet buoyancy assays.

Diet	CTRL-KD	Spen-KD	Area difference	P-value
	AUC (A.U.)	AUC (A.U.)	Spen-KD–CTRL-KD
MYD	399.3	494	94.70 ± 11.75	<0.0001
HYD	407	479	72.00 ± 12.71	<0.001
HSD	478	540.9	62.90 ± 10.01	<0.0001
HFD	515.9	587.4	71.50 ± 7.558	<0.0001

Area difference is reported with confidence interval. Two-way ANOVA analysis compared Spen-KD and CTRL-KD in matched diets (see File S1). n = 5, A.U., arbitrary units.