Table 3. Life span, in median days elapsed to death, of male and mated female Spen-KD and CTRL-KD genotypes in control and EXPs.

Sex	Diet	CTRL-KD survival (median days)	CTRL-KD (MYD|EXP) chi-square	P-value	Spen-KD survival (median days)	Spen-KD (MYD|EXP) chi-square	P-value	Cliff’s delta (d)
Female	MYD	68	NA	NA	37	NA	NA	NA
	HYD	71.5	0.02097	ns	31	56.81	<0.0001	0.62
	HSD	67	4.349	0.037	43	38.35	<0.0001	−0.12
	HFD	2	120.5	<0.0001	6	136.7	<0.0001	−0.54
Male	MYD	48.5	NA	NA	50	NA	NA	NA
	HYD	45	0.9183	ns	42	90.88	<0.0001	0.37
	HSD	55	6.227	0.013	50	1.188	ns	0.27
	HFD	18	105.0	<0.0001	11	129.0	<0.0001	0.12

Cliff’s delta (d) shows effect size of diet on genotype. n = 3 replicates, 20 flies per replicate. Chi-square from log-rank (Mantel–Cox) test.