Table 3.

Requirements of the immune exposure model

Exposure process type	Exposure material	Disease name	Disease stage
Vaccination	Required	None	None
Infectious challenge	Required	Optional	Optional
Transplantation	Required	None	None
Infectious disease	Required	Required	Required
Allergic disease	Required	Required	Required
Autoimmune disease	None	Required	Required
Cancer	None	Required	Required
Asymptomatic infection	Required	None	None
Exposure with immune reactivity	Required	None	None
Documented exposure	Required	None	None
Exposure to ubiquitous agent	Required	None	None