Table 3:
EDTT model for detecting AEs in the ED
| Event Frequencies (95% CI) | Lasso | ||||
|---|---|---|---|---|---|
| Trigger | RR (95%CI) | Trigger present | Trigger absent | weight | |
| L6 | pCO2 >60 | 5.3 (3.4–8.2) | 41.2% (25.9–57.9) | 7.8% (6.6– 9.1) | 0.67 |
| C7 | BiPAP/CPAP | 4.7 (3.0–7.4) | 36.8% (22.9–52.7) | 7.8% (6.6– 9.1) | -- |
| C3 | Restraint use | 4.6 (3.4–6.4) | 31.6% (23.6–40.5) | 6.8% (5.7– 8.1) | 0.88 |
| C39 | Aspiration | 4.5 (2.6–7.8) | 36.0% (19.5–55.5) | 8.0% (6.8– 9.3) | 0.38 |
| M7 | TPA | 4.3 (2.5–7.5) | 34.6% (18.7–53.7) | 8.0% (6.8– 9.3) | 1.08 |
| C4 | SBP <90 x2 | 4.1 (3.0–5.7) | 27.2% (20.7–34.5) | 6.6% (5.4– 7.9) | 0.69 |
| C13 | O2 <90% | 4.0 (3.0–5.5) | 25.2% (19.6–31.6) | 6.3% (5.1– 7.5) | 0.63 |
| P6 | Central line insertion | 4.0 (2.8–5.8) | 29.4% (20.5–39.7) | 7.3% (6.2– 8.7) | -- |
| P2 | Intubation | 3.9 (2.8–5.4) | 26.8% (20.0–34.6) | 6.9% (5.7– 8.2) | -- |
| M5 | D50 | 3.8 (2.3–6.3) | 30.0% (17.6–45.2) | 7.9% (6.7– 9.2) | -- |
| P8 | US guided IV | 3.8 (2.3–6.1) | 29.5% (17.7–44.0) | 7.9% (6.7– 9.2) | 0.65 |
| M3 | Heparin | 3.6 (2.3–5.6) | 27.9% (17.8–40.0) | 7.7% (6.5– 9.0) | 0.53 |
| C19 | RR <10 or >24 | 3.5 (2.6–4.7) | 17.9% (14.6–21.6) | 5.2% (4.1– 6.5) | 0.35 |
| M9 | Nitroglycerin / Nicardipine / Nitroprusside | 3.4 (2.1–5.5) | 26.5% (15.8–40.0) | 7.9% (6.7– 9.2) | 0.12 |
| C42 | Acute dialysis | 3.3 (1.9–5.7) | 26.3% (14.4–41.7) | 8.0% (6.8– 9.4) | -- |
| L8 | Cr >2.0 or BUN >30 | 3.1 (2.3–4.2) | 20.3% (15.6–25.8) | 6.6% (5.4– 7.9) | 0.39 |
| M18 | Opiates + benzo | 3.1 (2.2–4.4) | 22.2% (16.2–29.1) | 7.1% (5.9– 8.4) | 0.22 |
| C53 | SIRS criteria | 3.0 (2.2–4.2) | 13.8% (11.4–16.4) | 4.5% (3.4– 5.9) | 0.08 |
| M4 | Benadryl | 3.0 (2.0–4.6) | 23.1% (15.3–32.5) | 7.6% (6.4– 8.9) | 1.32 |
| L11 | BNP >300 | 3.0 (1.9–4.8) | 23.6% (15.0–34.3) | 7.8% (6.6– 9.1) | -- |
| L2 | Lactate >4 | 2.9 (1.9–4.3) | 21.8% (14.6–30.6) | 7.6% (6.4– 8.9) | -- |
| M17 | IV Calcium | 2.9 (1.8–4.6) | 22.4% (13.7–33.4) | 7.9% (6.7– 9.2) | -- |
| C27 | SBP>180; DBP >120 | 2.8 (2.1–3.8) | 18.0% (14.0–22.6) | 6.4% (5.3– 7.7) | 0.53 |
| L7 | Troponin >.03 | 2.8 (2.0–3.9) | 19.9% (14.5–26.2) | 7.1% (6.0– 8.5) | -- |
| L4 | Glucose <60 or >300 | 2.8 (1.9–4.1) | 20.7% (14.2–28.5) | 7.5% (6.3– 8.8) | 0.29 |
| C20 | Temp. <35 or >38 C | 2.8 (1.8–4.4) | 21.8% (14.2–31.4) | 7.7% (6.5– 9.1) | -- |
| C8 | HR>130 | 2.7 (1.8–3.9) | 19.7% (13.9–26.7) | 7.4% (6.2– 8.7) | -- |
| C48 | IV anti-hypertensives | 2.4 (1.6–3.6) | 18.4% (12.1–26.3) | 7.7% (6.5– 9.1) | -- |
| C30 | ED Boarding >6hrs | 2.0 (1.4–2.8) | 14.7% (10.8–19.4) | 7.3% (6.1– 8.7) | -- |
| C6 | ED LOS >6hours | 1.9 (1.4–2.7) | 10.5% (8.8–12.5) | 5.5% (4.0– 7.3) | 0.43 |
The complete table is provided in Supplemental Table S2.
RR: Relative risk, the ratio of columns (3) an (4), with 95% confidence interval.
Event Freqs: Unadjusted risk of ED AE, given presence (col 3) and absence (col 4) of that trigger. Other triggers may be present.
Lasso: Weight given from a lasso predictive model, if retained. These weights are used later to calculate an overall score, indicative of risk of occurrence of an ED AE