Table 4:
Comparison of tumor characteristics of early-onset CRC vs. late-onset CRC
| Variable | Early-onset, known n | Early-onset, n (%) | Late-onset, known n | Late-onset, n (%) | Univariable Pa |
|---|---|---|---|---|---|
| Site | 79 | 463 | .02 | ||
| Right colon | 20 (25) | 190 (41) | |||
| Left colon | 32 (41) | 162 (35) | |||
| Rectum | 27 (34) | 111 (24) | |||
| Stage | 83 | 460 | .01 | ||
| Early stage | 19 (23) | 173 (38) | |||
| Late stage | 64 (77) | 287 (62) | |||
| Grade | 73 | 412 | .53 | ||
| Low grade | 58 (80) | 343 (83) | |||
| High grade | 15 (21) | 69 (17) | |||
| KRAS mutation | 98 | 47 (48) | 49 | 20 (41) | .52 |
| MSI | 117 | 7 (6) | 56 | 10 (18) | .03 |
Abbreviations: MSI: microsatellite instability
a
Chi-squared and Fisher exact tests were used for analysis.