Table 3:
The minimum inhibitory concentration (MIC, μg/ml) of turmeric’s derivatives and control anticlostridial drugs against normal microflora.
| Strain ID | Curcumin | Bisdemethoxycurcumin | Demethoxycurcumin | Tetrahydrocurcumin | Curcumol | Fidaxomicin | Vancomycin | Metronidazole |
|---|---|---|---|---|---|---|---|---|
| Bacteroides fragilis HM-711 | >128 | 32 | 64 | >128 | 128 | >128 | 8 | 1 |
| Lactobacillus casei ATCC® 334 | >128 | >128 | >128 | >128 | >128 | 4 | >128 | >128 |
| Lactobacillus gasseri HM-641 | >128 | >128 | >128 | >128 | >128 | ≤1 | ≤1 | >128 |
| Lactobacillus gasseri HM-400 | 64 | >128 | 64 | >128 | 128 | ≤1 | 8 | >128 |
| Lactobacillus gasseri HM-407 | 32 | >128 | 128 | 128 | >128 | ≤1 | ≤1 | >128 |
| Bifidobacterium longum HM-848 | >128 | >128 | >128 | >128 | >128 | ≤1 | ≤1 | 64 |
| Bacteroides dorei HM-719 | >128 | 128 | 128 | >128 | >128 | >128 | 16 | ≤1 |
| Bifidobacterium longum HM-846 | >128 | >128 | >128 | 64 | >128 | ≤1 | 1 | >128 |
| Bifidobacterium bifidum ATCC-11863 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 |
| Lactobacillus crispatus HM-103 | >128 | >128 | >128 | >128 | >128 | ≤1 | ≤1 | >128 |