Table 2.
The Correlation Between the Expression of Serum circFoxO3a and Clinicopathological Factors
| Variable | Low Expression of circFoxO3a (n=51) |
High Expression of circFoxO3a (n=52) |
P |
|---|---|---|---|
| Age, y (mean ± SD) | 0.105 | ||
| ≤45 | 11 | 18 | |
| >45 | 40 | 34 | |
| Stage | 0.881 | ||
| I | 36 | 36 | |
| II | 15 | 16 | |
| Surgery Type | 0.652 | ||
| Laparoscopy | 48 | 49 | |
| Laparotomy | 3 | 3 | |
| Tumor size | 0.059 | ||
| ≤4cm | 31 | 40 | |
| >4cm | 20 | 12 | |
| Lymphovascular invasion | 0.181 | ||
| Negative | 19 | 25 | |
| Positive | 32 | 27 | |
| Stromal invasion depth | 0.005 | ||
| <1/2 | 12 | 26 | |
| ≥1/2 | 39 | 26 | |
| Lymph node metastasis | 0.008 | ||
| Negative | 29 | 42 | |
| Positive | 22 | 10 | |
| Parametrial invasion | 0.347 | ||
| Negative | 46 | 49 | |
| Positive | 5 | 3 | |
| Margin | 0.491 | ||
| Negative | 48 | 50 | |
| Positive | 3 | 2 | |
| HPV infection | 0.188 | ||
| Negative | 4 | 8 | |
| Positive | 47 | 44 | |
| Ki-67 | 0.166 | ||
| Low (≤35%) | 13 | 14 | |
| Median (≤70%) | 29 | 35 | |
| High (>70%) | 9 | 3 |