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. 2020 Mar 25;35(3):305–320. doi: 10.1007/s10654-020-00623-6

Table 6.

Variables measured in NYU CHES through child age 2 years

< 18 weeks 18–25 weeks > 25 weeks Birth 4–7 months 8–11 months 12–17 months 18–23 months 24–35 months
Maternal/family characteristics
 Family sociodemographic factors Q, EHR EHR Q Q Q Q Q
 Gestational hypertension, preeclampsia and gestational diabetes Q, EHR Q, EHR EHR Q Q
 Current pregnancy information, including morning sickness and vitamin/medication use Q Q Q
 Maternal stress, depression, or anxiety Q Q Q Q Q Q
 Adverse events during pregnancy EHR EHR EHR Q
 Reproductive history Q, EHR EHR EHR
 General health and health history Q, EHR Q, EHR Q, EHR Q Q
 Sleep Q Q Q
 Physical activity Q Q Q Q
 Maternal substance use Q Q Q Q Q Q Q Q
 Housing characteristics Q Q Q Q
 Home environment Q
 Pets and pests Q Q Q Q Q Q Q
 Maternal social support, exposure to domestic violence Q Q Q
 Diet Q
 Labor and delivery of previous birth, and previous pregnancies Q, EHR Q, EHR
 Maternity leave/employment Q Q Q Q
 Childcare Q Q Q Q
 Food insecurity Q Q
 Parenting and family cohesion Q
Child characteristics
 Diet and feeding Q Q Q Q
 General health, medications, and hospitalizations Q, EHR Q, EHR Q, EHR Q, EHR Q, EHR
 Early development Q Q Q Q Q
 Language development Q
 Emotional and behavioral development Q Q
 Floor time and devices that hold the baby Q Q Q
 Media exposure Q Q Q Q Q
 Sleep Q Q Q Q
Clinical measures
 Fetal sonographic measurements Measured Measured Measured
 Brachial artery distensibility, blood pressure M:Measured

M:Measured

C:Measured

 Weight and height

M:Q, EHR

P:Q

M:EHR M:EHR

M:Q, EHR

C:Q, EHR

C:Q C:Q C:Q

M:Measured

C:Measured

M:Measured

C:Measured

 Anogenital distance Measured Measured Measured
 Fat, lean mass (DXA scan) C:Measured C:Measured
Biological measures
 Bisphenols, phthalate metabolites, dialkylphosphate metabolites, polycyclic aromatic hydrocarbon metabolites M:Urine M:Urine M:Urine C:Urine C:Urine
 Biomarkers of oxidant stress M:Urine M:Urine M:Urine C:Urine C:Urine
 Metabolomics M:Urine M:Urine M:Urine C:Urine C:Urine
 Adiponectin and leptin Cord serum
 Thyroid function and Thyroid peroxidase antibody M:Serum
 Biomarkers of inflammation and endothelial dysfunction M:Serum M:Serum M:Serum Cord serum
 Sex steroids M:Serum
 Methylomics (genome-wide) Cord PAXgene
 Transcriptomics (genome-wide) Cord PAXgene

Q questionnaire as completed by mothers, EHR electronic health record, C child, M maternal, P partner