Table 1.
Demographics of human study subjects. Caucasian stone-formers and healthy non-stone formers were recruited as described in the Materials and Methods section. Outpatient 24 h urines were collected on random ad lib outpatient diets and urinary stone risk profile was assayed by the Clinical Laboratory Improvement Amendments (CLIA)-certified laboratory and genotyping was performed by the Sequencing Core at the Pak Center of Mineral Metabolism and Clinical Research (Reed et al., 2002).
| Non-stone formers | Stone formers | |||||
|---|---|---|---|---|---|---|
| WT | R621G–Het | V206M–Het | WT | D23H–Het D673N–Het |
V206M–Het | |
| Ethnicity (NH/H)* | 20/1 | 1/0 | 2/0 | 18/0 | 1/0 | 8/1 |
| Gender (M/F) | 7/14 | 1/0 | 1/1 | 13/5 | 0/1 | 7/2 |
| Age, years | 45 ± 11 | 33 | 50 ± 7 | 44 ± 14 | 43 | 43 ± 14 |
| (Min–max) | (20–57) | (45–55) | (8–61) | (18–61) | ||
*All subjects are Caucasian.