Table 3.

Immunoglobulin heavy and light chain V gene usage in cold agglutinin disease and Waldenström macroglobulinemia.

Gene	Cold agglutinin disease	Waldenström macroglobulinemia/lymphoplasmacytic lymphoma
Heavy chain gene	IGHV4-34 (>85%) (5, 9, 28, 29)	IGHV3 (83%) (IGHV3-23, 24%) (5, 30)
Light chain gene	IGKV3-20 (59%) (29, 35)	Not determined