Table 2.
Univariate statistical comparison of pre-probiotic and probiotic cohorts.
| Pre-probiotic cohort | Probiotic cohort | p-value | Odds ratio 95% CI | |
|---|---|---|---|---|
| Number | 2,556 | 1,973 | ||
| Birth weight mean (SD) | 1,227 (373) | 1,235 (381) | 0.32 | |
| Gestation median (IQR) | 29 (4) | 29 (4) | 0.84 | |
| Male sex% | 54 | 53.6 | 0.74 | |
| Worst base excess (SD) | −3.9 (4.7) | −4.3 (4.5) | 0.37 (0.09 to 0.66) | |
| Apgar 1 min (IQR) | 6 (5–8) | 6 (4–8) | 0.003 | |
| Apgar 5 min (IQR) | 9 (8–9) | 8 (7–9) | <0.001 | |
| Admission temperature°C mean (SD) | 36.38 (0.73) | 36.48 (0.79) | <0.001 | |
| Breast milk at onset % | 81.9 | 93.4 | 0.32 (0.26 to 0.40) | |
| Birth weight z score mean (SD) | −0.095 (1.105) | −0.064 (1.118) | 0.36 | |
| NEC number (%) | 70 (2.7) | 35 (1.8) | 1.58 (1.04 to 2–6)* | |
| LOS number (%) | 348 (13.6) | 210 (10.6) | 1.32 (1.10 to 1.59)* |
CI, confidence interval;
*
, unadjusted; NEC, necrotizing enterocolitis; LOS, late onset sepsis.