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. 2020 Apr 7;8:119. doi: 10.3389/fped.2020.00119

Table 5.

Other neonatal outcomes in pre-probiotic and probiotic cohorts.

Pre-probiotic cohort Probiotic cohort OR (95%CI) p-value
Intubated at delivery % 37.9 36.6 0.37
IPPV hrs mean (SD) 184 (296) 161 (282) 0.001
CPAP hrs mean (SD) 552 (637) 552 (587) 0.27
High flow hrs mean (SD) 469 (380)
Days to regain birth weight (SD) 10.25 (5.25) 9.15 (4.2) <0.001
Chronic lung disease % 14.6 27.6 0.45 (0.39–0.52)
Home oxygen % 6.20 9.73 0.61 (0.49–0.77)
Treated ROP % 3.80 2.83 0.15
In-hospital mortality % 7.68 7.82 0.87
IVH any % 20.38 21.60 0.93 (0.78–1.10)
IVH grade 3 or 4 % 4.60 7.04 0.70(0.49–1.00)*
NEC <1,000 g % 5.9 4.8 1.25 (0.77–2.04)#
Late onset sepsis <1,000 g % 29.2 24.3 1.34 (1.04–1.72)$

IPPV, intermittent positive pressure ventilation; hrs, hours; CPAP, continuous positive airway pressure; ROP, retinopathy of prematurity; IVH, intra ventricular hemorrhage; NEC, necrotizing enterocolitis; SD, standard deviation; OR, odds ratio; CI, confidence interval.

*

Corrected for gestation, antenatal steroid use, sex, birth weight z score, ethnicity, birth hospital.

#

Corrected for birth weight, sex, birth weight z score.

$

Corrected for gestation, PPROM.