Table 5.
Other neonatal outcomes in pre-probiotic and probiotic cohorts.
Pre-probiotic cohort | Probiotic cohort | OR (95%CI) | p-value | |
---|---|---|---|---|
Intubated at delivery % | 37.9 | 36.6 | 0.37 | |
IPPV hrs mean (SD) | 184 (296) | 161 (282) | 0.001 | |
CPAP hrs mean (SD) | 552 (637) | 552 (587) | 0.27 | |
High flow hrs mean (SD) | – | 469 (380) | ||
Days to regain birth weight (SD) | 10.25 (5.25) | 9.15 (4.2) | <0.001 | |
Chronic lung disease % | 14.6 | 27.6 | 0.45 (0.39–0.52) | |
Home oxygen % | 6.20 | 9.73 | 0.61 (0.49–0.77) | |
Treated ROP % | 3.80 | 2.83 | 0.15 | |
In-hospital mortality % | 7.68 | 7.82 | 0.87 | |
IVH any % | 20.38 | 21.60 | 0.93 (0.78–1.10) | |
IVH grade 3 or 4 % | 4.60 | 7.04 | 0.70(0.49–1.00)* | |
NEC <1,000 g % | 5.9 | 4.8 | 1.25 (0.77–2.04)# | |
Late onset sepsis <1,000 g % | 29.2 | 24.3 | 1.34 (1.04–1.72)$ |
IPPV, intermittent positive pressure ventilation; hrs, hours; CPAP, continuous positive airway pressure; ROP, retinopathy of prematurity; IVH, intra ventricular hemorrhage; NEC, necrotizing enterocolitis; SD, standard deviation; OR, odds ratio; CI, confidence interval.
Corrected for gestation, antenatal steroid use, sex, birth weight z score, ethnicity, birth hospital.
Corrected for birth weight, sex, birth weight z score.
Corrected for gestation, PPROM.