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. 2020 Apr 7;10:380. doi: 10.3389/fonc.2020.00380

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Copyright © 2020 Yang, Jiang, Yao, Wang, Sun, Qin and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Disease-related indicators before and after neoadjuvant chemotherapy for colorectal cancer. (A) Hematoxylin-eosin (HE) staining showing the tumor-stroma ratio before and after neoadjuvant chemotherapy. Immunohistochemical staining of GALC (B), Ki67 (C), p53 (D), and E-cadherin (E) was performed to explore the relationship between these markers and prognosis. p < 0.05 was considered statistically significant.