| 1 Preterm prelabour rupture of membranes |
1 |
229 |
Risk Ratio (M‐H, Random, 95% CI) |
0.31 [0.06, 1.49] |
| 1.1 Unselected pregnant women |
1 |
229 |
Risk Ratio (M‐H, Random, 95% CI) |
0.31 [0.06, 1.49] |
| 1.2 High‐risk pregnant women |
0 |
0 |
Risk Ratio (M‐H, Random, 95% CI) |
0.0 [0.0, 0.0] |
| 2 Preterm delivery |
6 |
3663 |
Risk Ratio (M‐H, Random, 95% CI) |
0.88 [0.72, 1.09] |
| 2.1 Unselected pregnant women |
4 |
2905 |
Risk Ratio (M‐H, Random, 95% CI) |
0.97 [0.82, 1.15] |
| 2.2 High‐risk pregnant women with BV and weight before pregnancy less than 50 kg |
1 |
81 |
Risk Ratio (M‐H, Random, 95% CI) |
0.41 [0.18, 0.97] |
| 2.3 High‐risk pregnant women with BV and weight before pregnancy more than 50 kg |
1 |
177 |
Risk Ratio (M‐H, Random, 95% CI) |
0.68 [0.49, 0.93] |
| 2.4 High‐risk pregnant women with previous preterm delivery |
2 |
500 |
Risk Ratio (M‐H, Random, 95% CI) |
1.08 [0.66, 1.77] |
| 3 Preterm delivery in all high‐risk pregnancy |
2 |
758 |
Risk Ratio (M‐H, Random, 95% CI) |
0.89 [0.58, 1.36] |
| 3.1 High‐risk pregnant women with BV and weight before pregnancy less than 50 kg or greater than 50 kg |
1 |
258 |
Risk Ratio (M‐H, Random, 95% CI) |
0.64 [0.47, 0.88] |
| 3.2 High‐risk pregnant women with previous preterm delivery |
2 |
500 |
Risk Ratio (M‐H, Random, 95% CI) |
1.08 [0.66, 1.77] |
| 4 Puerperal sepsis/postpartum endometritis |
3 |
627 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.53 [0.35, 0.82] |
| 4.1 Unselected pregnant women |
2 |
431 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.51 [0.24, 1.08] |
| 4.2 High‐risk pregnant women; history of preterm delivery, LBW < 2500 g, stillbirth or early perinatal death |
1 |
196 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.55 [0.33, 0.92] |
| 5 Low birthweight |
4 |
978 |
Risk Ratio (M‐H, Random, 95% CI) |
0.86 [0.53, 1.39] |
| 5.1 Unselected pregnant women |
3 |
725 |
Risk Ratio (M‐H, Random, 95% CI) |
1.07 [0.71, 1.63] |
| 5.2 High‐risk pregnant women; history of preterm delivery, LBW < 2500 g, still birth or early neonatal death |
1 |
253 |
Risk Ratio (M‐H, Random, 95% CI) |
0.57 [0.37, 0.88] |
| 6 Neonatal sepsis |
1 |
142 |
Risk Ratio (M‐H, Fixed, 95% CI) |
11.31 [0.64, 200.79] |
| 6.1 Unselected pregnant women |
0 |
0 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 6.2 High‐risk pregnant women; with previous preterm delivery |
1 |
142 |
Risk Ratio (M‐H, Fixed, 95% CI) |
11.31 [0.64, 200.79] |
| 7 Prelabour rupture of membranes |
1 |
229 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.34 [0.15, 0.78] |
| 7.1 Unselected pregnant women |
1 |
229 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.34 [0.15, 0.78] |
| 7.2 High‐risk pregnant women |
0 |
0 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 8 Chorioamnionitis |
1 |
229 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.62 [0.10, 3.62] |
| 8.1 Unselected pregnant women |
1 |
229 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.62 [0.10, 3.62] |
| 8.2 High‐risk pregnant women |
0 |
0 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 9 Gonococcal infection; postpartum detected (not prespecified) |
1 |
204 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.35 [0.13, 0.94] |
| 9.1 Unselected pregnant women |
0 |
0 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 9.2 High‐risk pregnant women |
1 |
204 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.35 [0.13, 0.94] |
| 10 Compliance |
1 |
229 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.87 [0.76, 1.00] |
| 10.1 Unselected pregnant women |
1 |
229 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.87 [0.76, 1.00] |
| 10.2 High‐risk pregnant women |
0 |
0 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 11 Mean gestational age (weeks) |
1 |
253 |
Mean Difference (IV, Fixed, 95% CI) |
0.70 [0.01, 1.39] |
| 11.1 Unselected pregnant women |
0 |
0 |
Mean Difference (IV, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 11.2 High‐risk pregnant women |
1 |
253 |
Mean Difference (IV, Fixed, 95% CI) |
0.70 [0.01, 1.39] |
| 12 Mean birthweight |
4 |
978 |
Mean Difference (IV, Random, 95% CI) |
41.60 [‐78.20, 161.40] |
| 12.1 Unselected pregnant women |
3 |
725 |
Mean Difference (IV, Random, 95% CI) |
9.08 [‐123.61, 141.77] |
| 12.2 High‐risk pregnant women |
1 |
253 |
Mean Difference (IV, Random, 95% CI) |
155.0 [6.22, 303.78] |
| 13 Congenital abnormality |
2 |
463 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.49 [0.20, 11.14] |
| 13.1 Unselected pregnant women |
2 |
463 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.49 [0.20, 11.14] |
| 13.2 High‐risk pregnant women |
0 |
0 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 14 Small‐for‐gestational age |
1 |
229 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.29 [0.42, 3.96] |
| 14.1 Unselected pregnant women |
1 |
229 |
Risk Ratio (M‐H, Fixed, 95% CI) |
1.29 [0.42, 3.96] |
| 14.2 High‐risk pregnant women |
0 |
0 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.0 [0.0, 0.0] |
| 15 Perinatal mortality |
4 |
2710 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.83 [0.57, 1.20] |
| 15.1 Perinatal mortality in unselected women |
2 |
2315 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.84 [0.57, 1.23] |
| 15.2 High‐risk pregnant women with history of preterm delivery, LBW < 2500 g, stillbirth or perinatal death |
1 |
253 |
Risk Ratio (M‐H, Fixed, 95% CI) |
0.53 [0.13, 2.18] |
| 15.3 High‐risk pregnant women with previous preterm delivery |
1 |
142 |
Risk Ratio (M‐H, Fixed, 95% CI) |
3.08 [0.13, 74.46] |
