| Methods |
Randomisation list was generated by computer.
Double blind
77 participants randomised, 59 analysed. |
| Participants |
Inclusion: history of Grade 2 or Grade 3 dysmenorrhoea for at least 4 cycles, regular menstrual cycles, pelvic exam to confirm no pathology, no older than 32 years old.
Exclusion: secondary dysmenorrhoea, suspected pregnancy, drugs use, sexually transmitted disease.
Age: mean 24.2 +/‐ 4.9
Location: USA |
| Interventions |
1. 21 days of desogestrel 0.15mg, ethinyl estradiol 0.02mg followed by 2 days of placebo and 5 days of ethinyl estradiol 0.01mg
2. Placebo
Duration: 4 cycles |
| Outcomes |
Pain severity (5 point scale) |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Low risk |
Computer generated list |
| Allocation concealment? |
Low risk |
A ‐ Adequate |
| Blinding?
All outcomes |
Low risk |
Double |
| Incomplete outcome data addressed?
All outcomes |
Low risk |
|
| Free of selective reporting? |
Unclear risk |
No adverse events |
| Power calculations |
High risk |
|
| Dropouts reported |
Low risk |
25/77 (14 from the desogestrel group and 11 from the placebo group) |
| Baseline comparability |
Low risk |
|
