| Methods |
Randomisation method not stated.
Open trial ‐ no blinding used.
1016 women initially randomised, 182 drop outs ( bleeding irregularities, adverse effects, ).
213 of the initial group randomised had dysmenorrhoea, with 173 women with dysmenorrhoea analysed. |
| Participants |
Inclusion: regular menstrual cycles (24‐35 days cycles), aged 18‐45 years old, BMI of 18‐29 kg/m2
Exclusion: smokers, contraindications to OC use, drugs use, women who had just given birth or had an abortion.
Age: DSG group ‐ 26.2, GSD group ‐ 26.3
Location: France |
| Interventions |
1. Ethinyl estradiol 0.02mg, 0.15mg desogestrel
2. Ethinyl estradiol 0.02mg, 0.075mg gestodene
Duration: 6 cycles. |
| Outcomes |
Dysmenorrhoea (mild, moderate, severe) |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Adequate sequence generation? |
Unclear risk |
No data provided |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
| Blinding?
All outcomes |
High risk |
|
| Incomplete outcome data addressed?
All outcomes |
Unclear risk |
No data provided |
| Free of selective reporting? |
Unclear risk |
No adverse events |
| Power calculations |
Low risk |
|
| Dropouts reported |
Low risk |
182/1016 (85 from desogestrel and 97 from gestodene group) |
| Baseline comparability |
Low risk |
|
